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The effects of protein corona on the interactions of AIE-visualized liposomes with ce
Using home-made aggregation-induced-emission-visualized nanoliposomes TR4@Lipo as a mode, prof. Liang and colleagues from NCNST reported that the protein corona can switch the interaction of cationic liposomes with cells from energy-independent membrane fusion to energy-dependent endocytosis. This work will promote a better understanding of bio-nano interaction at the interface level and will guide the utilization of nanoliposomes in the future.
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Scientists identify mechanism linking traumatic brain injury to neurodegenerative disease
Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases.
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Mass of human chromosomes measured for the first time
For the study, published in Chromosome Research, researchers used a powerful X-ray beam at the UK's national synchrotron facility, Diamond Light Source, to determine the number of electrons in a spread of 46 chromosomes which they used to calculate mass.
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Study: Parler provided echo chamber for vaccine misinformation, conspiracy theories
Researchers in the University of Kansas School of Journalism analyzed posts from new social media platform Parler regarding COVID-19 vaccine development which showed posters used an echo-chamber type approach to share misinformation on the vaccines. The findings can help shape future vaccine and health communications, they argue.
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COVID-positive people have more severe strokes, Geisinger-led study finds
Among people who have strokes and COVID-19, there is a higher incidence of severe stroke as well as stroke in younger people, according to new data from a multinational study group on COVID-19 and stroke, led by a team of Geisinger researchers.
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Taking a bite out of tooth evolution: Frogs have lost teeth more than 20 times
Florida Museum of Natural History researchers analyzed CT scans of nearly every living amphibian genus to reveal that frogs have lost teeth over 20 times during their evolution, more than any other vertebrate group.
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More salmonella infections in Europe: Hygiene rules help prepare poultry safely
In recent months, more than three hundred cases of salmonellosis have occurred in various European countries and Canada, which are linked to each other. In the UK the cases could be partly traced back to frozen breaded poultry meat. The cause was contamination with the bacterium Salmonella Enteritidis, which causes gastrointestinal inflammation. Salmonella is not killed by deep freezing and can remain infectious at temperatures below zero degrees Celsius.
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Foster care, homelessness are higher education hurdles
A college education is estimated to add $1 million to a person's lifetime earning potential, but for some students the path to earning one is riddled with obstacles. That journey is even more difficult for students who have been in the foster care system or experienced homelessness, according to a new study from the University of Georgia.
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Mini bone marrow model predicts response to blood disorder treatment
A new miniature 3D model of human bone marrow has been described today in the open-access eLife journal. The model may help clinicians predict which patients will benefit from a new therapy for blood platelet disorders, such as Inherited Thrombocytopenias -- a group of familial disorders that inhibit the production of platelets. It could also enable further study of these disorders and give scientists a new tool to test experimental treatments.
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How news coverage affects public trust in science
News media reports about scientific failures that do not recognize the self-correcting nature of science can damage public perceptions of trust and confidence in scientific work, according to findings of a study by researchers at the Annenberg Public Policy Center of the University of Pennsylvania and the University at Buffalo, the State University of New York.
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Trust among corvids
Corvids use social information to protect themselves against deception by conspecifics from neighboring territories.
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How the major Swedish forest fire of 2014 affected the ecosystem
Swedish researchers from institutions including Uppsala University have spent four years gathering data from the areas affected by the major forest fire of 2014. In their study of how the ecosystem as a whole has been altered, they could see that water quality in watercourses quickly returned to normal, while forested areas continued to lose carbon for many years after the fire.
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2D natural clay offers a platform for machine learning algorithm
The first 2D mica resistive random access memory (RRAM) device has been demonstrated, which exhibit unique non-Markov chain characteristic. The migration of inner K+ in mica under electrical field is responsible for this unique transport behavior. Our work shows great potential of 2D mineral materials for electronics.
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Early bird or night owl? Study links shift worker sleep to 'chronotype'
Getting enough sleep can be a real challenge for shift workers affecting their overall health. But what role does being an early bird or night owl play in getting good rest? Researchers from McGill University find a link between chronotype and amount of sleep shift workers can get with their irregular schedules.
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Best of both worlds: High entropy meets low dimensions, opens up infinite possibilities
Scientists at Tokyo Institute of Technology (Tokyo Tech) created a novel type of material that combines the structural flexibility of van der Waals materials with the endless tuning possibilities of high-entropy alloys. In their paper, they explore the properties of these new materials and the many promises they hold in electronics applications.
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Researchers develop proof-of-concept treatment that elevates adult and fetal hemoglobin
Researchers at Children's Hospital of Philadelphia (CHOP) have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal and adult hemoglobin. Using a viral vector engineered to reactivate fetal hemoglobin production, suppress mutant hemoglobin, and supply functional adult hemoglobin, the researchers developed an approach that could produce more hemoglobin through a single vector. The results were published in Haematologica.
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Manipulating quinary charge states in solitary defects of 2D intermetallic semiconductor
Creating and manipulating multiple charge states of a single atomic defect in semiconductors is of essential importance to "qubits" of solid-state quantum computation, but fundamentally limited by Coulomb's law. The object is challenged by the conflicting requirements of localization for sizable band gap and delocalization for low charging energy. Recently, researchers from China and Singapore realized exotic quinary charge states of single defect in two-dimensional intermetallic semiconductor Sn2Bi, and observed an ultralow defect charging energy.
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Story tips: Un-Earthly ice, buildings in the loop, batteries unbound and 3D printing for geothermal
ORNL story tips: Un-Earthly ice, buildings in the loop, batteries unbound and 3D printing for geothermal.
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Treatabolome project designed to shorten diagnosis-to-treatment time for patients with rare diseases
The Treatabolome project is a research initiative to develop a freely available, interoperable online platform to disseminate rare disease and gene-specific treatment information to healthcare professionals regardless of their level of specialized expertise to reduce treatment delays. This initiative is highly relevant to neuromuscular disorders as they are rare diseases by definition. In this special issue of the Journal of Neuromuscular Diseases, experts contribute Treatabolome-feeding systematic literature reviews on rare neurological and neuromuscular disorders.
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Researchers Fine-Tune Control Over AI Image Generation
Researchers have developed a new state-of-the-art method for controlling how artificial intelligence (AI) systems create images. The work has applications for fields from autonomous robotics to AI training.
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