Hamilton, ON (February 26, 2020) - McMaster University researchers have identified an antibacterial compound made by cannabis plants that may serve as a lead for new drug development.
An interdisciplinary team of McMaster researchers found that the chemical compound, or cannabinoid, called cannabigerol (CBG) is not only antibacterial but also effective in mice against a resilient family of bacteria known as methicillin-resistant Staphylococcus aureus (MRSA).
The findings were published in the journal American Chemical Society Infectious Diseases.
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.
Michael F. Vaezi, MD, PhD, MSc, director of the Center for Swallowing and Esophageal Disorders at Vanderbilt University Medical Center (VUMC), is corresponding author of the report published in the journal Gastroenterology. The study was conducted by Cambridge, Mass.-based Ironwood Pharmaceuticals.
As metropolises balloon with growth and sprawl widens the footprint of cities around the world, access to nature for people living in urban areas is becoming harder to find.
If you're lucky, a pocket park might be installed next to a new condominium complex on your block, or perhaps a green roof tops the building where you work downtown. But it's unusual to find places in a city that are relatively wild -- even though our evolutionary history suggests we need interactions with wild nature to thrive.
Many satellites are in space to take photos. But a vibrating satellite, like a camera in shaky hands, can't get a sharp image. Pointing it at a precise location to take a photo or perform another task, is another important function that requires accuracy. Vedant, an aerospace engineering doctoral student at the University of Illinois at Urbana-Champaign was working on a way to eliminate vibrations on a satellite when he discovered his invention could also rotate the satellite.
Forget what you know about bile because that's about to change, thanks to a new discovery made by Michigan State University and published in the current issue of Nature.
Much of our knowledge about bile hasn't changed in many decades. It's produced in the liver, stored in our gall bladder and injected into our intestine when we eat, where it breaks down fats in our gut. In fact, the first bile acid was discovered in 1848, and the scientists who revealed the structure of bile acids in 1928 won the Nobel Prize. That's a long time ago.
Oncotarget Volume 11 Issue 8 features Figure 8, "MLN4924 treatment induces DNA damage by stabilizing CDT1 and accumulates the cells in S phase which are enhanced by MLN4924/cisplatin co-treatment," by Misra, et al.
Moreover, adding MLN4924 to the standard TNBC chemotherapeutic agent cisplatin increased the DNA damage level, further enhancing the sensitivity.
CHICAGO (February 26, 2020): The best approach for surgeons to identify malnourished cancer patients before they have a cancer operation may be specifically related to the type of cancer the patient has, according to researchers who found that common definitions of malnutrition do not apply equally to all cancers in assessment of preoperative risk. The study is published as an "article in press" on the Journal of the American College of Surgeons website ahead of print.
CHAMPAIGN, Ill. -- With a new CRISPR gene-editing methodology, scientists from the University of Illinois at Urbana-Champaign inactivated one of the genes responsible for an inherited form of amyotrophic lateral sclerosis - a debilitating and fatal neurological disease for which there is no cure. The novel treatment slowed disease progression, improved muscle function and extended lifespan in mice with an aggressive form of ALS.
The aggravating skin condition eczema is most commonly treated by suppressing the immune system, but not all patients get relief. Now, a drug strategy aimed at revving up the immune system and boosting a type of immune cell known as natural killer cells appears, at least in mice, to effectively treat eczema.
The innovative approach, from researchers at Washington University School of Medicine in St. Louis, may point to a potential treatment for the skin condition, as well as other health problems linked to it, including asthma.
When a water droplet lands on a surface it can splash, coat the surface cleanly, or in special conditions bounce off like a beach ball
Droplets only bounce when the speed of collision with a surface is just right, creating a very thin nanoscale air cushion for it to rebound off
Drop collision is integral to technology such as 3D printing and spray cooling of next-generation electronics, and understanding this can help future developments in these fields