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Scientists from RUDN University jointly with their colleagues from Yaroslavl have developed a new way to synthesize 1,2,4-oxadiazole derivatives present in many drugs. 1,2,4-oxadiazoles include ataluren, the active ingredient of the drug used in genetic disorders treatment. The results of the work are published in the Tetrahedron Letters journal.

AMES, Iowa - The concept of "collective intelligence" is simple - it asserts that if a team performs well on one task, it will repeat that success on other projects, regardless of the scope or focus of the work. While it sounds good in theory, it doesn't work that way in reality, according to an Iowa State University researcher.

Cancer can most often be successfully treated when confined to one organ. But a greater challenge lies in treating cancer that has metastasized, or spread, from the primary tumor throughout the patient's body. Although immunotherapy can be effective in treating the metastatic phase of the disease, it is still applicable to a limited number of patients.

Nearly half of all US medical care is delivered by emergency departments, according to a new study by researchers at the University of Maryland School of Medicine (UMSOM). And in recent years, the percentage of care delivered by emergency departments has grown. The paper highlights the major role played by emergency care in health care in the U.S.

Access to gender-affirming surgery has improved in British Columbia over the past couple of years, but transgender people needing to access surgery still face complex and often unclear pathways, according to a new study from the Stigma and Resilience Among Vulnerable Youth Centre (SARAVYC) at UBC.

Yokohama, Japan - Oct. 17, 2017 - Small cell lung cancer (SCLC) biopsy specimen was found to be reliable material for evaluating DLL3 expression; high levels of DLL3 in SCLC are correlated with poor survival trends. Dr. Li-Xu Yan of Guangdong General Hospital and Guangdong Academy of Medical Sciences in China presented her findings from this study today at the International Association for the Study of Lung Cancer (IASLC) 18th World Conference on Lung Cancer (WCLC) in Yokohama, Japan.

Yokohama, Japan - Oct. 17, 2017 - New research shows that treating stage II and III non-small cell lung cancer (NSCLC) N+ resected patients with customized chemotherapy (CT) treatment based on their specific BRCA1 expression levels, as opposed to providing the standard treatment, did not increase overall survival rates among those patients who received individualized CT treatment. However, BRCA1 expression levels could be prognostic and treatment could achieve different outcomes. Dr.

Yokohama, Japan - Oct. 17, 2017 - The findings of a recent study confirm the International Association for the Study of Lung Cancer (IASLC)'s proposed criteria for uncertain resection margin status, R(un), in residual tumor (R) classification. Dr. John Edwards of the University of Sheffield in the United Kingdom presented his team's findings today at the IASLC 18th World Conference on Lung Cancer (WCLC) in Yokohama, Japan.

ORLANDO, Fla. - Oct. 17, 2017 - The sensitivity and reliability of Droplet Digital PCR will be showcased in over a dozen presentations at the American Society of Human Genetics (ASHG) 2017 Annual Meeting, Orlando, Fla., October 17-21. The breadth and diversity of the posters and plenaries demonstrate the impact Droplet Digital PCR technology has had throughout genomics.

Most - and possibly all - ovarian cancers start, not in ovaries, but instead in the fallopian tubes attached to them.

This is the finding of a multicenter study of ovarian cancer genetics led by researchers from Perlmutter Cancer Center at NYU Langone Health, and published online Oct. 17 in Nature Communications.