Body

Genetic testing is commonplace for many inheritable cancer syndromes, and with that comes the knowledge of being a gene carrier for some patients. Many guidelines recommend that gene carriers take certain steps, such as surgery, to reduce their risk of developing cancer. A new BJS (British Journal of Surgery) review explores the quality-of-life consequences of genetic testing and risk-reducing surgery.

Hannover and Amsterdam, Jan. 17, 2018 - Inflammation of the liver can result from different causes. Besides infections with hepatitis B virus (HBV) and hepatitis C virus (HCV), other viruses such as cytomegalovirus (CMV) are able to trigger acute hepatitis. Sometimes hepatitis induces fever and flu-like symptoms, however, it may also damage the liver and might even result in acute liver failure. Yet, currently there is no general agreement on how acute hepatitis should be treated: Should the immune response against the viral pathogen be reinforced or inhibited?

New Rochelle, NY, Jan. 17, 2018--In the 10th anniversary year since a bone marrow stem cell transplant cured Timothy Ray Brown of his HIV infection, despite disappointment over decreasing public desire to find a cure for HIV, Timothy Ray Brown remains optimistic that the scientific and medical communities can and will achieve this if properly funded.

AUGUSTA, Ga. (Jan. 17, 2018) - Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating or even preventing it.

Sophia Antipolis, 17 January 2018: Nearly a quarter of patients with chronic ischaemic cardiovascular disease are dead or hospitalised within six months, reports a European Society of Cardiology (ESC) study published today in the European Journal of Preventive Cardiology.1

Frequently encountered in the elderly, Alzheimer's is considered a neurodegenerative disease, which means that it is accompanied by a significant, progressive loss of neurons and their nerve endings, or synapses. A joint French and Canadian study published in Scientific Reports now challenges this view.

MADISON - While testing genes to treat glaucoma by reducing pressure inside the eye, University of Wisconsin-Madison scientists stumbled onto a problem: They had trouble getting efficient gene delivery to the cells that act like drains to control fluid pressure in the eye.

Genes can't work until they enter a cell.

DARIEN, IL - January 16, 2018 - Results of a randomized controlled trial suggest that systematic bright light exposure can improve sleep for fatigued people who have been treated for cancer.

Older adults are more likely than younger adults to develop critical illnesses that require hospitalization and intensive care.

DNA is like the computer code of the body, and it must be preserved for our bodies to survive. Yet, as cells grow and change, DNA is vulnerable to defects, especially double strand breaks (DSBs). In fact, DSBs regularly occur throughout one's lifetime. The DNA is protected, however, by DNA repair machinery. A new study from scientists at Osaka University and The University of Tokyo describes the crystal structure of a crucial part of this machinery, the binding of RNF168 to ubiquitylated proteins and find a unique binding not seen in other ubiquitylated protein interactions.