ROSEMONT, Ill. (Sept. 19, 2017) -- Osteoarthritis (OA) is a progressive "wear and tear" disease of the joint. Osteoarthritis of the knee (knee OA) may not be totally preventable but according to Elizabeth Matzkin, MD, an orthopaedic surgeon specializing in sports medicine with Brigham and Women's Hospital, there are some key factors that we can control to minimize the chances of developing bone and joint pain. So, what's the best treatment option for those who already have knee OA? Dr.

Data released today from the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) show that the HIV epidemic is coming under control in Lesotho. These results add to prior PEPFAR-supported Population-based HIV Impact Assessments (PHIAs) announced in the last nine months for Malawi, Swaziland, Zambia, and Zimbabwe.

The discovery of a puddle of mouse urine seems like a strange scientific "eureka" moment.

However, for one team of researchers, that's exactly what led to a new discovery.

The researchers' findings may enhance understanding of how our bodies balance water content -- 50 to 60 percent of our weight. It may also lead to better understanding of hormone-related diseases can cause conditions ranging from diabetes to obesity.

Researchers at the Center for Vascular Research, within the Institute for Basic Science (IBS), have identified a new mechanism involved in the development and progression of glaucoma, and found a potential therapeutic option to treat it. Glaucoma is the second cause of irreversible blindness, after cataracts. It affects about 3.5% of the world population aged 40 to 80. This study, published in the Journal of Clinical Investigation, is expected to help the development of therapies to treat primary open-angle glaucoma (POAG), which counts for three quarters of all glaucoma patients.

(Boston)-- A recent study has identified a new lung cell type that is implicated in the body's innate immune defense against the bacteria Streptococcus pneumoniae--one of the leading causes of pneumonia worldwide.

The findings, which appear in the Journal of Clinical Investigation, may lead to new, non-traditional approaches in the fight against pneumonia and chronic lung diseases.

Transradial catheterization--when a clinician inserts a long thin tube through the radial artery in the arm--is commonly used to diagnose and treat certain heart conditions. A recent analysis of published studies indicates that the procedure can have a significant detrimental effect on cells in the radial artery, which persists for at least several months post-catheterization. The analysis if published in the Journal of Cardiac Surgery.

PHILADELPHIA (Sept. 18, 2017) - Everybody wants a healthy life for their baby. Black babies are more likely to be born prematurely, which puts them at risk for death and developmental problems. In fact, a third of all infant deaths are preterm-related. The critical period in preterm babies' lives is when they are just born and are in the neonatal intensive care unit (NICU). The care they receive is vital to a healthy future.

DURHAM, N.C. -- Poor sleep is both a risk factor, and a common symptom, of depression. But not everyone who tosses and turns at night becomes depressed.

Individuals whose brains are more attuned to rewards may be protected from the negative mental health effects of poor sleep, says a new study by Duke University neuroscientists.

The researchers found that college students with poor quality sleep were less likely to have symptoms of depression if they also had higher activity in a reward-sensitive region of the brain.

PHILADELPHIA (September 18, 2017) - African-American men who have sex with men (MSM) remain at heightened risk for HIV infection and account for the largest number of African-Americans living with HIV/AIDS. It has long been understood that there is a clear and persistent association between poverty, transactional sex behavior, and HIV risk. A new University of Pennsylvania School of Nursing (Penn Nursing) study has investigated how educational status relates to HIV risk in this population.

Transgender and gender-nonconforming (TGNC) individuals often encounter discrimination that may compel them to seek mental health services, but some mental health practitioners are inadequately prepared to work with TGNC clients. Researchers have now presented an in-depth examination of the counseling experiences of 13 TGNC individuals to inform mental health practitioners of helpful and effective counseling methods.