PHILADELPHIA - (April 12, 2018) - Wistar researchers have identified a novel therapeutic vulnerability in NRAS mutant melanoma and an effective strategy to address it, using a combination of two clinically relevant inhibitors, according to study results published online in EMBO Molecular Medicine.
Discovered accidentally over a century ago, the phenomenon of superconductivity continues to inspire a technological revolution. In 1911, while studying the behavior of solid mercury supercooled to 4 K (-269 °C), Dutch physicist Heike Kamerlingh Onnes (1853-1926) observed for the first time that certain materials conducted electricity with neither resistance nor losses at temperatures in the vicinity of absolute zero.
URBANA, Ill. - When a natural disaster strikes, major disaster databases tend to compile information about losses such as damages to property or cost of repairs, but other economic impacts after the disaster are often overlooked--such as how a company's lost ability to produce products may affect the entire supply-chain within the affected region and in other regions.
Our emotional state in a given moment may influence what we see, according to findings published in Psychological Science, a journal of the Association for Psychological Science. In two experiments, researchers found that participants saw a neutral face as smiling more when it was paired with an unseen positive image.
BLOOMINGTON, Ind. -- At a time when more Americans are living longer, the companies where many people spend their working lives have increasingly shorter lifespans, according to research from Indiana University's Kelley School of Business.
A paper by two Kelley professors, forthcoming in the Academy of Management Annals, found that the odds of a company surviving more than five years has declined dramatically since the 1960s and that this trend also holds for firms lasting 10, 15 and 20 years.
SAN FRANCISCO, CA--April 10, 2018--Over a decade ago, Shinya Yamanaka and Kazutoshi Takahashi made a discovery that would revolutionize biomedical research and trigger the field of regenerative medicine. They learned how to reprogram human adult cells into cells that behave like embryonic stem cells. Scientists were shocked that something so complex could be done so simply, and they had thousands of questions.
ANN ARBOR--The child welfare system is more likely to intervene in households in "less neighborly" neighborhoods and in which parents spank their kids, a new study shows.
Researchers at the University of Michigan and Michigan State University conducted analyses on nearly 2,300 families from 20 large U.S. cities who responded to surveys and interviews. Participating families had a child who was born between 1998-2000.
A new way to rapidly assess levels of consciousness in people with head injuries could improve patient care.
The new score - based on the Glasgow Coma Scale - could also help doctors assess the health of the patient's central nervous system in cases of serious trauma or intensive care.
Using it could improve the way doctors around the world care for patients in a coma from brain injury.
The Glasgow Coma Scale (GCS), which was created at the University of Glasgow and the city's Southern General Hospital in 1974.
Transmissible cancers are incredibly rare in nature, yet have arisen in Tasmanian devils on at least two separate occasions. New research from the University of Cambridge identifies key anti-cancer drugs which could be trialled as a treatment for these diseases, which are threatening Tasmanian devils with extinction.
The research also found that the two Tasmanian devil transmissible cancers are very similar to each other, and likely both arose due to susceptibilities inherent to the devils themselves.
Electrical activity in a region of the parietal cortex underlies the detection of a transition between two complex sounds, finds a study of human participants published in eNeuro. The research provides insight into how the brain tunes into relevant changes in the environment to optimize behavior.