Researchers at the National Institutes of Health and other institutions have found a second genetic defect that accounts for previously unexplained forms of osteogenesis imperfecta (OI), a disorder that weakens bones, sometimes results in frequent fractures and is sometimes fatal.
Mice engineered to have cleft palates can be rescued in utero by injecting the mothers with a small molecule to correct the defect, say scientists at the Stanford University School of Medicine and Lucile Packard Children's Hospital. In addition to shedding light on the biology of cleft palate, the research raises hopes that it may one day be possible to prevent many types of human birth defects by using a similar vaccination-type technique in pregnant women likely to have affected fetuses.
Aggressive research currently underway brings hope of dramatic advances in breast cancer management, according to a new review. Published in the March 15, 2007 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the review reveals that new approaches in breast cancer imaging, investigations into the timing of chemotherapy, and research on breast cancer vaccines may lead to exciting new nonsurgical tools for the physician treating breast cancer patients.
Being a green consumer is hard work, according to new research funded by the Economic and Social Research Council (ESRC). The study highlights a need for more practical help and incentives for green consumers, if we are to achieve a more sustainable society.
A University of Florida-led study has determined that Titanis walleri, a prehistoric 7-foot-tall flightless “terror bird,” arrived in North America from South America long before a land bridge connected the two continents.
Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. And they did it using one of the most sinister pathogens around — HIV.
Insects and other flying animals are somehow able to maintain appropriate flying heights and execute controlled takeoffs and landings despite lacking the advantage of sophisticated instrumentation available to human aviators. By characterizing the behavior of a specially designed flying robot, researchers have now been able to test a theory that helps explain how visual cues are used by insects during flight to ensure appropriate distance from the ground.
Intradiscal biacuplasty is an effective procedure to treat chronic discogenic pain, report researchers at the 23rd annual meeting of the American Academy of Pain Medicine in New Orleans. Improvement in pain scores and functional capacity can be observed much earlier with intradiscal biacuplasty than with intradiscal electrothermal therapy suggesting some additional or/and different mechanisms of action. It also appears to be more effective than intradiscal electrothermal therapy producing more than 50% of the pain relief in more than 50% of patients.
Researchers have identified new genetic variations that may be associated with the risk of developing nonfatal venous thrombosis in postmenopausal women, according to a study in the February 7 issue of JAMA.
Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells.