CAMBRIDGE, Mass. -- Scientists at Harvard University and the University of Texas at Austin have found that genetic evolution is strongly shaped by genes' efforts to prevent or tolerate errors in protein production.

Their study also suggests that the cost of errors in protein production may lie in the malformed proteins themselves, rather than the loss of functional proteins. Misfolded proteins can build up in long-lived cells, like neurons, and cause neurodegenerative diseases.

Irvine, Calif. — UC Irvine researchers have found a molecular link between circadian rhythms – our own body clock – and metabolism. The discovery reveals new possibilities for the treatment of diabetes, obesity and other related diseases.

Paolo Sassone-Corsi, Distinguished Professor and Chair of Pharmacology, and his colleagues have identified that an essential protein called CLOCK that regulates the body's circadian rhythms, works in balance with another protein called SIRT1 that modulates how much energy a cell uses.

MINNEAPOLIS / ST. PAUL (July 24, 2008) – A multi-institutional team of researchers, including scientists at the University of Minnesota Medical School, have developed a powerful tool for genomic research and medicine. The robust method will allow researchers to generate synthetic enzymes that can target and manipulate DNA sequences for inactivation or repair.

Glasses embedded with a telescope promise to make it easier for people with impaired vision to drive and do other activities requiring sharper distance vision. Schepens Eye Research Institute scientists describe the advantages of these innovative glasses over earlier devices in an article published in the May/June issue of Journal of Biomedical Optics, mailed in print form to subscribers this month.

Basel, 24 July 2008. The European Committee for Human Medicinal Products (CHMP) has confirmed that the presence of an impurity called ethyl methanesulfonate (EMS) in Roche's Viracept (nelfinavir mesylate) did not increase patients' risk of developing cancer.

The discovery of the EMS impurity in some batches of nelfinavir led to a global recall of this HIV medication in June 2007. Since then, the product has been made available again in the EU.

Isoforms from Novel Structure Proteins (NSP), a new family of genes discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University's College of Science and Technology, could be involved in apoptosis or programmed cell death.

Chicago, 24 July 2008 –The editors of Neurotherapeutics are pleased and proud to announce their July issue, devoted to "Novel Therapeutics for Alzheimer's Disease." Neurotherapeutics ( is the journal of the American Society of Experimental NeuroTherapeutics (ASENT)

Age-dependent macular degeneration (AMD) is the commonest cause of blindness in the western industrialised nations. Hereditary changes in the regulation of the immune system influence the risk of contracting AMD. Opthalmologists at the University Clinic in Bonn, working in co-operation with researchers from Göttingen, Regensburg and Great Britain, have now, for the first time, demonstrated that in cases of senile blindness the patient´s immune resistance is hyperactive throughout his entire body.

Dr Szu-Yao (Zoe) Wang, who recently completed her PhD with UQ's School of Nursing, found that in Taiwan, where the culture dictates that children should care for their parents, aged-care facilities are becoming more popular.

"Family caregivers in Taiwan may experience criticism from a society which has a traditional cultural reticence about placing parents into a nursing home, as such action is considered contrary to filial piety," Dr Wang said.

PORTLAND, Ore. July 23, 2008. A fire is currently burning through a study area where projections were made about fire behavior about 2 years ago. Managers used data and analysis from the Gotchen Late-Successional Reserve (LSR) study in the planning, analysis, and implementation of treatments near where the Cold Springs fire is now active.